Topicals & Transdermals

Our Contribution:

3V Sigma USA offers a variety of leading Rheology Modifiers used in chemical formulations for the Topicals & Transdermals Industry.  We offer a selection of ISO9001 and GMP-certified products to meet the needs of a variety of applications.  Please visit our product portfolio to learn more about the solutions we provide to the Topicals & Transdermals Market.

General Market Information:

Rheology modifiers are commonly used in the topicals and transdermals market to adjust the viscosity, flow, and texture of formulations, thereby improving their application, stability, and performance.

In topicals, rheology modifiers can be used to control the consistency and spreadability of creams, gels, and ointments. This can enhance the product’s ability to adhere to the skin and to be absorbed through the various layers of the skin. For example, thickeners such as carbomers, cellulose derivatives, and polyacrylates can be used to increase the viscosity and yield stress of formulations, making them more suitable for topical application.

In transdermals, rheology modifiers can be used to control the rate of drug release and to enhance skin penetration. By adjusting the viscosity and flow properties of transdermal patches and gels, manufacturers can optimize the diffusion and absorption of the active ingredients through the skin, while also ensuring that the patch or gel remains in place and does not leak or detach from the skin. For example, hydrophilic polymers such as polyethylene glycol (PEG) can be used to improve the skin permeation of transdermal drugs, while hydrophobic polymers such as ethylene vinyl acetate (EVA) can be used to control the rate of drug release.

In both topicals and transdermals, rheology modifiers can also be used to stabilize the formulation and to prevent separation or settling of ingredients over time. This can help to maintain the quality and effectiveness of the product throughout its shelf life.

Overall, rheology modifiers are an important class of additives in the Topicals and Transdermals market, helping to optimize the formulation and performance of these products, while also improving the user experience and enhancing patient compliance.


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